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Bioanalytical Services
Contact Us
Email: info@pharmoptima.com
Phone: 269-329-4370
In Vitro Metabolism
- In vitro metabolism assessment
~Microsomal evaluation~Hepatocyte metabolism~Expressed cell metabolism- Assessment of the metabolic profile for determination of the metabolic routes(s) of metabolism and the CYP isozyme
- CYP drug-drug interaction assessment
- Enzyme induction/inhibition studies
- Plasma protein binding assessment
In Vivo Metabolism
Absorption, distribution, metabolism, excretion (ADME) in vivo assessment both with or without radiolabeled compounds.
Pharmacokinetics Analysis
- Preclinical pharmacokinetics
- PK/PD assessment
- Toxicokinetic assessment
- Investigations of absorption and clearance
- Bioavailability/bioequivalence
- Ocular PK
- Cassette (N in 1) dosing and analysis
Discovery ADME
Fast turn-around of studies and expert consultation for early "Discovery ADME"
Bioanalytical Team Leader
