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In Vivo Services
PharmOptima expedites many phases of the drug discovery process by providing expert consultation and laboratory support from the point of target selection to drug candidate selection. A key service provided by PharmOptima is our In Vivo services, which efficiently evaluates key compounds identified through in vitro screening. The screened compounds can then be tested for in vivo bioavailability, metabolism, phramacologic efficacy, and tolerance in models designed to meet your drug target needs. These in vivo services include:
- Ocular PK
- Preparation of novel drug formulations for local or systemic administration
- Design and implementation of experimental drug models
- KKAy diabetic mouse
- Cuprizone demyelination
- Evaluation of drug tolerance including cardiovascular, renal and CNS endpoints
- Devising sensitive pharmacodynamic (PD) parameters
- Integration of studies with drug delivery and pharmacokinetics (PK)
- Correlation of efficacy with drug exposure to establish PD/PK relationships
- Analysis of data generated both within and outside of PharmOptima
Contact PharmOptima for more information on both standard and customized In Vivo models
Contact Us
Email: info@pharmoptima.com
Phone: 269-329-4370
Specialized Capabilities
Ocular pk including collection of:
- trabecular meshwork
- ciliary bodies
- Iris
- Aqueous humor
- Choroid (central and/or peripheral)
- Retina (central and/or peripheral)
Surgery
