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Services
PharmOptima provides consulting and laboratory services and develops customized solution for your drug discovery, formulation and in vivo profiling problems. Let us help you with:
- In vitro ADME including microsomal and cellular metabolic profiling, isozyme characterization, p450 inhibition and protein binding
- In vitro metabolite identification and production service
- Proof of concept testing for pharmacologic efficacy, tolerance and ADME
- In vivo proof of concept testing and model development to confirm drug delivery, efficacy, and tolerance
- In vivo ADME; establishing bioanalytical assays using HPLC /MS-MS and other methods, pharmacokinetic studies, PK/PD analyses, and GLP sample analysis
- Ocular PK including trabecular meshwork, ciliary body and aqueous humor
- Intratracheal instillation
- Immunoassays (ELISA) and biochemical spectrophotometric assays
PharmOptima's services add value to the drug discovery process:
- Optimizing screening assays and ensuring identification of authentic leads
- Early identification of a compound's biochemical mechanism of action
- Providing initial proof of concept testing in animals for compound bioavailability, tolerance and ADME
Clients save time and money by identifying problems with their drug candidates early, before investing in costly in vivo safety and first-in-human testing.
Additional Information on...
Contact Us
Email: info@pharmoptima.com
Phone: 269-329-4370
